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Sun, Jul 27, 2025

RNAi

Home » Topics » Drugs » RNAi
  • Circode executives 7 11
    July 15, 2025
    By Marian (YoonJee) Chu

    Circode applies circRNA to heart disease drug R&D, in vivo CAR T

    Shanghai Circode Biomed Co. Ltd. is set to begin clinical trials of HM-2002, a circular RNA (circRNA)-based drug for ischemic heart disease, having gained IND clearance in China Jan. 10 and the U.S. on May 30, Circode CEO Chenxiang Tang recently told BioWorld.
  • Circode executives 7 11
    July 11, 2025
    By Marian (YoonJee) Chu

    Circode applies circRNA to heart disease drug R&D, in vivo CAR T

    Shanghai Circode Biomed Co. Ltd. is set to begin clinical trials of HM-2002, a circular RNA (circRNA)-based drug for ischemic heart disease, having gained IND clearance in China Jan. 10 and the U.S. on May 30, Circode CEO Chenxiang Tang recently told BioWorld.
  • Interfering rna (rnai)
    June 20, 2025

    New RNAi targets KRAS G12V using a cancer cell receptor

    An RNA interference (RNAi) molecule that selectively targets the KRAS G12V mutation could represent a key advance in the treatment of cancer associated with this oncogenic variant. Researchers at the University of North Carolina (UNC) at Chapel Hill, in collaboration with Enfuego Therapeutics Inc., have developed a new RNAi designed to enter cells through the epidermal growth factor receptor (EGFR), which is commonly overexpressed in tumor cells. This targeted entry pathway could minimize the side effects associated with therapies that affect KRAS.
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