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Sat, May 10, 2025

New compound

Home » Topics » Science » New compound
  • May 9, 2025

    Chinese researchers unveil new agent for KRAS G12D-mutated tumors

    The KRAS G12D mutation is the most common oncogenic KRAS variant, identified in approximately 34% of pancreatic ductal adenocarcinoma cases, 12% of colorectal cancers and 4% of lung adenocarcinomas.
  • 3d illustration of human digestive system
    May 7, 2025

    LM-350 shows strong antitumor activity in CDH17-positive models

    Cadherin 17 (CDH17) is a membrane-bound cell adhesion molecule involved in tumor cell proliferation and is selectively overexpressed in several gastrointestinal malignancies, including colorectal cancer, gastric cancer and pancreatic cancer.
  • May 6, 2025

    Novel PROTAC shows robust antitumor activity in preclinical models of prostate cancer

    Researchers from Jiangsu Hengrui Pharmaceuticals Co. Ltd. reported the discovery of SHR-3591, an orally bioavailable AR proteolysis targeting chimera (PROTAC) designed to treat prostate tumors.
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