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» PH027-1, a potent WRN inhibitor with a wide safety margin and efficacy against MSI-H tumors
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Cancer
PH027-1, a potent WRN inhibitor with a wide safety margin and efficacy against MSI-H tumors
April 10, 2024
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Researchers from Puhe Biopharma Co. Ltd. presented the discovery and preclinical evaluation of PH027-1, a novel small-molecule Werner syndrome protein (WRN) inhibitor targeting microsatellite instability high (MSI-H) tumors.
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