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» Anticancer quinolone yields antileukemia effects and overcomes venetoclax resistance
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Cancer
Anticancer quinolone yields antileukemia effects and overcomes venetoclax resistance
June 20, 2024
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Targeting topoisomerase 2 (TOP2) is crucial in AML, and researchers from Wakunaga Pharmaceutical Co. Ltd. have developed and tested racemic WAC-224, a quinolone TOP2 inhibitor, and (
R
)-WAC-224 as a potential approach for AML treatment.
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