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Cancer
HM-100760 targets MTAP-deleted cancers via synthetic lethality
Oct. 31, 2024
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Methionine adenosyltransferase 2A (MAT2A), the rate-limiting enzyme in the methionine cycle, catalyzes the formation of
S
-adenosylmethionine (SAM) from methionine and adenosine triphosphate (ATP).
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