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BioWorld - Monday, May 12, 2025
Home » HIV

Articles Tagged with ''HIV''

Blue gloved hand holding a syringe

Gilead PrEPs to add HIV profits as lenacapavir phase III scores

June 20, 2024
By Randy Osborne
Gilead Sciences Inc. tallied a “clear win,” said Barclays analyst Carter Gould, in the phase III interim analysis showing that the Foster City, Calif.-based company’s twice-yearly injectable HIV-1 capsid inhibitor, lenacapavir, yielded 100% efficacy as an HIV blocker for cisgender women.
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Vaccination

In HIV, vaccine-induced broadly neutralizing antibodies, and paths to more of them

May 22, 2024
By Anette Breindl
In a paper published in the May 17, 2024, online issue of Cell, investigators from the Duke Human Vaccine Institute reported that a sequence of three immunizations in the HVTN-133 trial was sufficient for the development of heterologous or broadly neutralizing antibodies that protected against several strains of HIV.
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Vaccination
HIV/AIDS

In HIV, vaccine-induced broadly neutralizing antibodies, and paths to more of them

May 21, 2024
By Anette Breindl
In a paper published in the May 17, 2024, online issue of Cell, investigators from the Duke Human Vaccine Institute reported that a sequence of three immunizations in the HVTN-133 trial was sufficient for the development of heterologous or broadly neutralizing antibodies (bnAbs) that protected against several strains of HIV. The findings are “a real beachhead,” Barton Haynes told BioWorld. Haynes is the director of the Duke Human Vaccine Institute and the senior author of the paper.
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DNA in drug capsules, digital background
Drug design, drug delivery & technologies

Grant funds vehicles to deliver DNA-encoded therapeutics

May 9, 2024
Nanite Inc. has been awarded a $1.8 million grant by the Bill & Melinda Gates Foundation to design and optimize polymeric delivery vehicles to deliver DNA-encoded therapeutics.
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HIV/AIDS

CoPoP liposomes presenting stabilized HIV-1 Env trimers elicit multiclade neutralization in rabbits

May 3, 2024
Novel HIV-1 vaccine strategies should elicit potent and broad immunity against the viral envelope (Env) glycoprotein. Particle presentation of Env has shown promise in animal studies, but has several problems that limit their clinical application.
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HIV/AIDS

Gilead Sciences presents viral replication inhibitors for HIV

May 2, 2024
Gilead Sciences Inc. has patented 4'-Thionucleoside analogues acting as viral replication inhibitors reported to be useful for the treatment of HIV infection.
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Colombia issues compulsory license for Viiv’s HIV drug Tivicay

April 26, 2024
By Karen Carey
The government of Colombia, after signaling its intent to do so at the end of 2023, issued a compulsory license on April 24 for access to generic versions of HIV drug dolutegravir, without the permission of patent owner Viiv Healthcare Ltd.
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HIV/AIDS

Chinese researchers patent new compounds for HIV

April 16, 2024
Scientists at Jisikai (Suzhou) Pharmaceutical Co. Ltd. and Yaopharma Co. Ltd. have disclosed polycyclic N-heterocyclic ketone compounds reported to be useful for the treatment of HIV infection.
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HIV-1 virus particle
HIV/AIDS

Autophagy gene polymorphism protects against HIV-1 disease pathogenesis

April 16, 2024
The autophagy process, a critical regulator of T-cell function, has been shown to control acute HIV-1 infection and play a crucial role also in HIV-1 disease pathogenesis.
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Rx, med-tech industry groups warn of impact of Gilead R&D suits

April 1, 2024
By Mari Serebrov
The U.S. biopharma and med-tech industries are adding their voice to that of Gilead Sciences Inc. in urging the California Supreme Court to review the Gilead Tenofovir Cases, which seek to hold the drug company liable for how and when it developed its pipeline of HIV drugs.
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