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Home » brain

Articles Tagged with ''brain''

Amygdala

As research reveals brain disease circuitry, targeting follows suit

Dec. 21, 2021
By Anette Breindl
Attempts to modernize the conceptual framework of brain function and dysfunction are one prerequisite for brain disorders to benefit from precision medicine. For the circuit-based insights that are slowly emerging to benefit patients, though, better targeting methods are needed.
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Neural network activity

Better treatments for brain disorders start with knowing what to treat

Dec. 20, 2021
By Anette Breindl
Brain disorders have not yet profited from advances in precision medicine to the same extent that other disorders have. With the advent of magnetic resonance imaging and other technologies, watching the brain at work has made great strides in recent decades. But those data have often been shoehorned into the categories of the Diagnostic and Statistical Manual of Mental Disorders. Researchers are working to bring diagnostic categories in line with a modern understanding the brain.
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Spintech’s MRI enhancement technology gets FDA nod

Aug. 10, 2021
By Meg Bryant
The FDA has given the green light to Spintech Inc. for its STAGE (strategically acquired gradient echo) magnetic resonance imaging device. The post-processing software platform allows MRI technicians to capture higher-quality brain images in significantly less time than standard approaches.
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Stem cell-derived cerebral organoid
ISSCR 2020

‘Hope, hype and hubris’ of brain organoids on display at stem cell meeting

June 26, 2020
By Anette Breindl
Technical challenges at the annual meeting of the International Society for Stem Cell Research (ISSCR) meeting led to at least one lively exchange of stem cell jokes in the chat box as the audience waited for talks to resume, including stem cell parental advice: “You can be anything you want when you grow up!”
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Sleep cartoon
Sleepless in Cambridge

Sleep deprivation kills through punch to the gut

June 16, 2020
By Anette Breindl
The disconnect between the need for sleep and the possession of a brain is what prompted Dragana Rogulja, an assistant professor of neurobiology in the Blavatnik Institute at Harvard Medical School, and her team to take a look at multiple tissues in sleep-deprived flies and mice.
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Sleep cartoon
Sleepless in Cambridge

Sleep deprivation kills through punch to the gut

June 5, 2020
By Anette Breindl
From memory formation to waste clearance, sleep, Dragana Rogulja said, is thought of as “of the brain, by the brain, for the brain.” However, sleep may be necessary for the brain, but the brain is not necessary for sleep.
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Brain organoids
‘Confused and disorganized’

Stress, identity crises part of growing up – for organoids

Jan. 29, 2020
By Anette Breindl
When developmental neurobiologist Arnold Kriegstein talks about his work, it sounds for all the world like he is talking about the brains of teenagers. They are stressed. Their identity is mixed up. But putting them in a good environment is helpful to their development. Kriegstein, though, was describing brain organoids.
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Neurons
Less is more

Rightsizing brain activity increases lifespan, but REST is not all good

Oct. 25, 2019
By Anette Breindl
Two very different roles were reported for the protein REST last week. In adults, REST activation appeared to extend lifespan by reducing overall brain activity. Principal investigator Bruce Yankner, professor of genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biology of Aging, told BioWorld that in postmortem brain samples of individuals who had had no cognitive impairments at the time of their death, his team found "a correlation between down-regulation of excitation and extended longevity."
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Harvard lab develops method to rapidly produce nanowires to monitor neuron activity

July 8, 2019
By Stacy Lawrence
Monitoring the electrical activity within and between cells on a large scale in a living animal may seem like a task that's next to impossible. But that's precisely what researchers at Cambridge, Mass.-based Harvard University aim to do with the next iteration of nanoscale sensors in the shape of wires.
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