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Home » depression

Articles Tagged with ''depression''

Woman taking medication for mental illness
Neurology/psychiatric

Targeting NEK7 relieves depression-like symptoms in rats

July 15, 2025
No Comments
A recent study published in the journal International Immunopharmacology presents compelling preclinical evidence that NIMA-associated kinase 7 (NEK7), a key regulator of inflammation, may play a pivotal role in the pathology of depression.
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Silhouette made of crumpled paper illustrating depression
Neurology/psychiatric

Enveric’s EB-003 shows statistically significant improvements in model of severe chronic depression

May 29, 2025
No Comments
Enveric Biosciences Inc. has released promising preclinical results for its lead neuroplastogen drug candidate, EB-003, in the open space forced swim test, a preclinical mouse model of severe depression and despair. In the first study, an oral dose of EB-003 at 30 mg/kg significantly reduced depression-like behavior within 30 minutes of administration.
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Sonomind ultrasounds brain stimulation system

Sonomind’s TUS device reduces depressive symptoms

May 14, 2025
By Shani Alexander
A low-intensity transcranial ultrasound stimulation device, developed by Sonomind SAS, was proven to be safe and effective in treating patients suffering from drug-resistant depression. The results of a study published in Brain Stimulation showed a 61% reduction in the depressive symptoms of patients treated with the device over a five-day period, with no serious adverse events.
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Illustration of scary hand overshadowing crouching girl
Neurology/psychiatric

Psychedelics modulate neuroimmune interactions that control fear

April 28, 2025
By Mar de Miguel
Research of the neuroimmune mechanisms involved in stress-related fear revealed how astrocytes interact with neurons in the amygdala. The study, led by Harvard scientists, also unveiled that this interaction recruited monocytes to the meninges during chronic stress and showed how psychedelic compounds reversed monocyte accumulation in the meninges and reduced fear behavior.
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Neurology/psychiatric

Suzhou Vigonvita Life Sciences patents new 5-HT1A receptor agonists

April 17, 2025
Suzhou Vigonvita Life Sciences Co. Ltd. has disclosed 5-HT1A receptor agonists reported to be useful for the treatment of neurological disorders.
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Neurology/psychiatric

Haisco Pharmaceutical describes new κ-opioid receptor antagonists

April 3, 2025
Haisco Pharmaceutical Group Co. Ltd. has identified κ-opioid receptor antagonists reported to be useful for the treatment of anxiety and depression.
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AI-generated art of brain connections
Neurology/psychiatric

Dissecting the role of neural circuits in mental health

March 31, 2025
By Mar de Miguel
In the brain, molecular information is transmitted between cells through neural circuits. Synapses establish connections between the pathways that run from one area to another, allowing the most complex organ in the body to fulfill different functions. Cells and neural circuits are the basic biological elements in the study of mental illness. However, the scientific community still does not know how to interpret their role in neuropsychiatric disorders.
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Female sitting on floor in dark room
Neurology/psychiatric

Novel TRPC4/5 inhibitor is anxiolytic and antidepressant

March 26, 2025
Researchers from Shanghai Institute of Materia Medica of the Chinese Academy of Sciences and China Pharmaceutical University presented the discovery of novel orally bioavailable inhibitors of transient receptor potential canonical channels 4 and 5 (TRPC4/5), being developed for the treatment of depression and anxiety.
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KIMES 2025
KIMES 2025

Trio of neuro disease-focused firms highlighted at KIMES 2025

March 25, 2025
By Marian (YoonJee) Chu
At the four-day KIMES 2025 exhibition, more than 35,000 products and prototypes were on display. In the clamor, BioWorld engaged with three promising neurological disease-focused companies – Readycure Inc., Neurive Co. Ltd. and Vuno Inc. – that showcased innovative technology for conditions like Alzheimer’s disease and tinnitus at the Seoul-based event.
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Sooma device with laptop

Sooma receives IDE for neurostimulation therapy for depression

March 11, 2025
By Shani Alexander
Sooma Oy secured U.S. FDA investigational device exemption approval to initiate a pivotal study of its transcranial direct current stimulation medical device in people with major depressive disorder. The study will examine the efficacy of the non-invasive Sooma 2Gen device in improving MDD as an at-home treatment.
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