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Home » GLP-1

Articles Tagged with ''GLP-1''

Man measuring waist

Obesity data stir excitement for Novo Nordisk’s oral amycretin

March 7, 2024
By Karen Carey
Phase I data of oral amycretin, a co-agonist of GLP-1 and amylin receptors from Novo Nordisk A/S, showed a 13.1% reduction in body weight at 12 weeks vs. 1.1% for placebo, pushing shares of the Bagsvaerd, Denmark-based company to their highest levels to date.
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Feet on scale and measuring tape

Me-two drug? Viking mid-stage trial wins with GLP-1/GIP bid

Feb. 27, 2024
By Randy Osborne
The enticing prospect – and proven worth – of dually agonizing the glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors gained more evidence in a big way from Viking Therapeutics Inc. with VK-2735 in a phase II weight loss study. Shares of San Diego-based Viking Therapeutics Inc. (NASDAQ:VKTX) closed Feb. 27 at $85.05, up $46.57, or 121%, as investors learned that the drug achieved the primary and all secondary endpoints in the phase II study called Venture, with significant body-weight drops at all doses compared to placebo.
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Boston Scientific OverStitch device

UK’s NICE recommends endoscopic sleeve gastroplasty as obesity treatment

Feb. 22, 2024
By Shani Alexander
The U.K.’s National Institute for Health and Care Excellence (NICE) has given people looking to lose weight another treatment option by recommending endoscopic sleeve gastroplasty (ESG) as a therapy to help treat obesity. The move comes amidst increasing awareness of the disease brought on by the growing prevalence of GLP-1 agonists.
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Grey dollar sign on grey background

$170M banked, Bioage phase II to test GLP-1/apelin combo

Feb. 13, 2024
By Randy Osborne
Bioage Labs Inc.’s $170 million series D financing will pay for phase II trials with azelaprag, an apelin receptor agonist, to be tried in combination with Zepbound (tirzepatide), the glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 (GLP-1) receptor agonist from Bioage partner Eli Lilly and Co.
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Novo Nordisk buying three fill-finish sites for Wegovy supply

Feb. 5, 2024
As Novo Nordisk A/S has struggled with supply of its GLP-1 drug Wegovy (semaglutide), its controlling shareholder, Novo Holdings A/S, has agreed to acquire global contract development and manufacturing organization Catalent Inc. and its more than 50 global sites for $63.50 per share in cash, about $16.5 billion.
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Allurion Balloon

Allurion’s swallowable gastric balloon introduced into the UK NHS

Jan. 25, 2024
By Shani Alexander
A U.K. national health service (NHS) hospital has begun offering Allurion Technologies Inc.’s swallowable gastric balloon to patients struggling to lose weight for surgery. The move is a boon for the company amid rising competition in the weight loss market from GLP-1 agonists.
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Coin stacks layered with charts

GLP-1 not all loss, sweet side emerges for med tech

Jan. 16, 2024
By Annette Boyle
Investors bailed on many med-tech companies last year, fearing that the frenzy surrounding GLP-1 agonists would tank companies in the weight-loss, diabetes and orthopedics segments. Their concerns now appear overblown in many instances, with some of the most directly affected businesses reporting a “rising tide” associated with an increased focus on obesity treatment that has lifted their boats rather than sinking them.
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Pills, bottle, scale and-measuring tape

Rhythm to acquire LG Chem’s rare genetic obesity drug for $305M

Jan. 9, 2024
By Marian (YoonJee) Chu
Rhythm Pharmaceuticals Inc. is picking up LG Chem Ltd.’s oral small-molecule drug, LB-54640, for potentially $305 million, effectively growing its MC4R pipeline that houses U.S. FDA-approved Imcivree (setmelanotide) for genetic obesity disorders.
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Concept art for diabetes, genetics.
Endocrine/Metabolic

Fractyl nominates candidate for type 2 diabetes

Jan. 8, 2024
Fractyl Health Inc. has nominated RJVA-001 as the first clinical type 2 diabetes candidate from its Rejuva gene therapy platform, which is designed to deliver locally administered genetic medicines to the pancreas.
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Pills, bottle, scale and-measuring tape

Rhythm to acquire LG Chem’s rare genetic obesity drug for $305M

Jan. 5, 2024
By Marian (YoonJee) Chu
Rhythm Pharmaceuticals Inc. is picking up LG Chem Ltd.’s oral small-molecule drug, LB-54640, for potentially $305 million, effectively growing its MC4R pipeline that houses U.S. FDA-approved Imcivree (setmelanotide) for genetic obesity disorders.
Read More
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