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Home » GLP-1

Articles Tagged with ''GLP-1''

Novo Nordisk buying three fill-finish sites for Wegovy supply

Feb. 5, 2024
As Novo Nordisk A/S has struggled with supply of its GLP-1 drug Wegovy (semaglutide), its controlling shareholder, Novo Holdings A/S, has agreed to acquire global contract development and manufacturing organization Catalent Inc. and its more than 50 global sites for $63.50 per share in cash, about $16.5 billion.
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Allurion Balloon

Allurion’s swallowable gastric balloon introduced into the UK NHS

Jan. 25, 2024
By Shani Alexander
A U.K. national health service (NHS) hospital has begun offering Allurion Technologies Inc.’s swallowable gastric balloon to patients struggling to lose weight for surgery. The move is a boon for the company amid rising competition in the weight loss market from GLP-1 agonists.
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Coin stacks layered with charts

GLP-1 not all loss, sweet side emerges for med tech

Jan. 16, 2024
By Annette Boyle
Investors bailed on many med-tech companies last year, fearing that the frenzy surrounding GLP-1 agonists would tank companies in the weight-loss, diabetes and orthopedics segments. Their concerns now appear overblown in many instances, with some of the most directly affected businesses reporting a “rising tide” associated with an increased focus on obesity treatment that has lifted their boats rather than sinking them.
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Pills, bottle, scale and-measuring tape

Rhythm to acquire LG Chem’s rare genetic obesity drug for $305M

Jan. 9, 2024
By Marian (YoonJee) Chu
Rhythm Pharmaceuticals Inc. is picking up LG Chem Ltd.’s oral small-molecule drug, LB-54640, for potentially $305 million, effectively growing its MC4R pipeline that houses U.S. FDA-approved Imcivree (setmelanotide) for genetic obesity disorders.
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Concept art for diabetes, genetics.
Endocrine/Metabolic

Fractyl nominates candidate for type 2 diabetes

Jan. 8, 2024
Fractyl Health Inc. has nominated RJVA-001 as the first clinical type 2 diabetes candidate from its Rejuva gene therapy platform, which is designed to deliver locally administered genetic medicines to the pancreas.
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Pills, bottle, scale and-measuring tape

Rhythm to acquire LG Chem’s rare genetic obesity drug for $305M

Jan. 5, 2024
By Marian (YoonJee) Chu
Rhythm Pharmaceuticals Inc. is picking up LG Chem Ltd.’s oral small-molecule drug, LB-54640, for potentially $305 million, effectively growing its MC4R pipeline that houses U.S. FDA-approved Imcivree (setmelanotide) for genetic obesity disorders.
Read More
Top Trends Therapeutics, pill, syringe

Obesity/overweight opportunities drive R&D and funding

Dec. 28, 2023
By Karen Carey
If there is one therapeutic area for which numerous biopharma companies and investors have shown increasing amounts of interest in 2023, it is obesity through follow-on glucagon-like peptide-1 receptor agonists, as well as combination and solo efforts with other potential mechanisms. Analysts have suggested the obesity market (which includes overweight individuals) could grow to more than $50 billion by 2030. At least.
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Wegovy

2023’s biggest breakthrough is not, unfortunately, in separating science from myth

Dec. 27, 2023
By Anette Breindl
In their year-end list of top scientific achievements and the people who made them, both Science and Nature have included the fight against “the obesity epidemic.” Science named GLP-1 drugs as its Breakthrough of the Year, while Nature included Svetlana Mojsov in its 2023 list of the year’s most important investigators. Mojsov is research associate professor at The Rockefeller University and was an early contributor to understanding the metabolic role of GLP.
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Stock chart with falling red arrow

Phase IIa data re-Structure hopes in oral GLP-1 effort

Dec. 18, 2023
By Randy Osborne
Given what CEO Raymond Stevens called a space that’s “evolving extremely rapidly,” Structure Therapeutics Inc. chose – rather than wait for next year’s 12-week data – to unblind the eight-week obesity findings with GSBR-1290, an oral glucagon-like peptide-1 (GLP-1) agonist for which the firm also provided a phase IIa update in patients with type 2 diabetes.
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GLP-1 muscle putting users in SARM’s way; myostatin, apelin bids also in the works

Dec. 14, 2023
By Randy Osborne
The advent of glucagon-like peptide-1 (GLP-1) receptor agonists has meant new hope for people with type 2 diabetes and obesity, but also has brought the challenge of muscle loss, which various drug developers are trying to ameliorate by way of mixed approaches.
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