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Home » ovarian cancer

Articles Tagged with ''ovarian cancer''

Cancer

Shenzhen Sungening Biotechnology discovers new KIF18A inhibitors

March 7, 2025
Shenzhen Sungening Biotechnology Co. Ltd. has described kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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Macrophage and cancer cell
Cancer

Macrophage-drug conjugate platform shows preclinical benefits for solid tumor therapy

Feb. 18, 2025
Solid tumors are difficult to treat due to their heterogeneity and limited blood supply, which restrict the effective delivery of anticancer drugs. Macrophages are abundant in solid tumor tissues and are the only cell type actively infiltrating hypoxic tumor regions, making them a promising option for delivering therapeutic agents directly to tumors.
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Ovarian cancer illustration
Cancer

Targeting TNIK-CDK9 axis is new strategy in ovarian cancer

Feb. 12, 2025
High-grade serous ovarian cancer (HGSC) is among the most lethal gynecologic malignancies, with up to 90% of patients eventually becoming resistant to platinum-based chemotherapy. The limited availability of effective targeted therapies for platinum-resistant HGSC presents a significant clinical challenge.
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Cancer

ZNFX1 identified as a tumor suppressor in ovarian cancer

Feb. 7, 2025
Tumor immune evasion mechanisms could be reversed by activating intracellular antiviral immune responses. It has been reported that the use of DNA methyltransferase (DNMT) inhibitors combined with poly(ADP ribose) polymerase (PARP) inhibitors activated stimulator of interferon genes (STING) signaling pathway in a process named pathogen mimicry response.
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Cancer

Targeting ApoB100 to treat ovarian cancer

Feb. 3, 2025
A group of researchers in China have looked into the role of apolipoprotein B100 (ApoB100) in ovarian cancer following reports of excessive levels of ApoB100 inducing endoplasmic reticulum stress and cell death in liver cancer and of a positive correlation between ApoB100 levels and survival time of patients with high-grade epithelial ovarian cancer.
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Cancer

CRL4 inhibition as a possible approach for treating ovarian cancer

Jan. 29, 2025
Researchers from the U.S. have discovered a new therapeutic target for the treatment of ovarian cancer.
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Cancer

Chia Tai Tianqing Pharmaceutical divulges new KIF18A inhibitors

Jan. 20, 2025
Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has synthesized kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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3d illustration of ovarian cancer
Immuno-oncology

ERNA-101 extends survival in mice with ovarian cancer

Jan. 15, 2025
Eterna Therapeutics Inc. has released promising results from a preclinical study of its lead cell therapy product, ERNA-101, showing it reduced tumor burden and extended survival in mice with ovarian cancer.
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AI-generated image for cancer cells observed under a microscope
Immuno-oncology

CSPC’s SYS-6041 cleared to enter clinic in China

Jan. 13, 2025
CSPC Pharmaceutical Group Ltd. has obtained clinical trial approval from China’s National Medical Products Administration (NMPA) for SYS-6041, an antibody-drug conjugate, for advanced solid tumors.
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Illustration of a cluster of ovarian cancer cells
Cancer

New AI-based models better than humans at diagnosing ovarian cancer

Jan. 7, 2025
By Shani Alexander
Artificial intelligence (AI)-based models developed by a team of international researchers were able to identify ovarian cancer in ultrasound images more accurately than humans. Results from a study published in Nature Medicine showed that the AI models achieved an accuracy rate of 86.3%, compared to 82.6% for the experts and 77.7% for the non-expert examiners.
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