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Home » biomarkers

Articles Tagged with ''biomarkers''

Pain illustration

BioSMART Center eyes development of sensors for pain

Jan. 11, 2021
By Mark McCarty
Pharmaceutical pain management has aided billions of patients, but has also created millions of cases of addiction, a problem that is driving research into pain. Omowunmi Sadik of the New Jersey Institutes of Technology, said on a recent webinar that the Biosensor Materials for Advanced Research & Technology (BioSMART) Center, is working on a suite of biosensors that may aid in the detection of the molecular markers associated with pain.
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Bluestar Genomics, University of Chicago see publication of 5hmC map

Dec. 2, 2020
By Liz Hollis
Bluestar Genomics Inc. and the University of Chicago revealed the publication of a genome-wide 5-hydroxymethylcytosine (5hmC) map across multiple human tissue types. In the report, published Dec. 2, 2020, in Nature Communications, the researchers detailed the development of the map by characterizing the genomic distributions of 5hmC in 19 human tissues derived from 10 organ systems.
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Colorectal cancer illustration

Test sensitivity, specificity debated in Medicare colorectal cancer biomarker coverage draft

Nov. 24, 2020
By Mark McCarty
The draft version of the U.S. Medicare national coverage analysis for blood-based biomarker tests for colorectal cancer (CRC) engendered a large body of support, but several stakeholders recommended that the Centers for Medicare & Medicaid Services (CMS) avoid prescriptiveness regarding the sensitivity and specificity for any tests that would be covered under the policy.
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Coronavirus-lungs-test-tube

Three new COVID-19 tests get much needed push from FDA and smart technology

Nov. 9, 2020
By David Godkin
TORONTO – Toronto-based Sqi Diagnostics Inc. has reported significant clinical progress developing three novel COVID-19 tests for submission for U.S. FDA emergency use authorization.
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OncoDNA CEO, Integragen CEO
Genomic profiling for tumors

Integragen subject to takeover by OncoDNA for $16.7M

Aug. 14, 2020
By Bernard Banga
PARIS – Integragen SA and OncoDNA SA have signed a tender offer agreement anticipating a takeover bid. Gosselies, Belgium-based OncoDNA will purchase 100% of the shares of Integragen, floated on the Euronext Paris Euronext Growth Markets, at a unit price of $2.60, valuing the latter’s share capital at $17.2 million.
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Ziva instrument in the lab

Adarza’s Ziva provides window into immune response to COVID-19 and other pathogens

June 23, 2020
By Annette Boyle
Adarza Biosystems Inc.’s Ziva platform can simultaneously detect hundreds of proteins, antibodies, or substrates from a single drop of blood, plasma or serum, providing insight into an individual’s immune response. That could be critical for both surveillance and diagnostic purposes as the nation prepares for a likely second wave of the novel coronavirus in the fall when multiple respiratory pathogens will be circulating.
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Celltracks system for Cellsearch

Companies on the hunt for biomarkers to predict highest risk COVID-19 patients

May 4, 2020
By Nuala Moran
LONDON – With COVID-19 infection varying in severity from asymptomatic to lethal the search is now underway for biomarkers to predict which patients are most at risk of suffering severe disease. As one possibility, Menarini Silicon Biosystems (MSB) is using its Cellsearch liquid biopsy technology to capture and count circulating endothelial cells. Meanwhile, Oxford Biodynamics plc is applying its Episwitch platform to find prognostic and predictive epigenetic markers.
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EEG testing
Decoding depression

EEG signature can predict response to SSRIs

Feb. 10, 2020
By Anette Breindl
For depression, and other mental health disorders, the era of precision medicine has yet to arrive. Symptoms are “very poorly reflective of the underlying biology,” Amit Etkin told BioWorld. Depression can manifest through multiple different symptoms that differ both between and within cultures.
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Silhouette with keyhole

Researchers use AI to identify longitudinal, blood-based neurodegenerative biomarkers

Jan. 30, 2020
By Stacy Lawrence
Early detection of neurodegenerative disease even before symptoms emerge is the ideal when it comes to trying to treat or prevent progression. But that has remained difficult, as brain tissue that isn’t available until after death is typically the most definitive. Now, researchers have used an artificial intelligence (AI) algorithm to identify genetic expression data over time and correlate them in blood and postmortem brain tissue samples from subjects with either Alzheimer’s or Huntington’s disease.
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Caris launches AI-based genomic profiling test to clarify cancer of unknown primary origin

Dec. 12, 2019
By Stacy Lawrence
Irving, Texas-based Caris Life Sciences Inc. has launched an AI-based genomic profiling test to better characterize cases of cancer of unknown primary origin (CUP) and atypical cases and offer appropriate treatment options. Known as the MI GPS (Genomic Profiling Similarity) Score, the analysis is based on an AI analysis of a 592-gene panel of all the clinically relevant genetic biomarkers for cancer.
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