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Home » colorectal cancer

Articles Tagged with ''colorectal cancer''

KRAS check: Cardiff prepares for take-off (or takeout?) with more data in mCRC

Jan. 19, 2022
By Randy Osborne
Treatment-emergent adverse events (TEAEs) may have soured investors on otherwise-positive new data from Cardiff Oncology Inc.’s phase Ib/II study with PLK1 inhibitor onvansertib in second-line, KRAS-mutated metastatic colorectal cancer (mCRC). Cardiff, however, is forging ahead with a pivotal experiment.
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Green approved stamp

Henlius bevacizumab biosimilar receives China marketing approval

Dec. 14, 2021
By Doris Yu
Shanghai Henlius Biotech Inc.’s self-developed Hanbeitai (bevacizumab biosimilar) has received marketing approval from China’s NMPA.
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Tot Biopharm’s first ADC bevacizumab gets China lung cancer approval

Dec. 7, 2021
By Doris Yu
Tot Biopharm International Co. Ltd.’s self-developed Pusintin (bevacizumab), a biosimilar to Roche Holding AG’s Avastin, has won marketing approval from China’s NMPA. It was approved for the treatment of patients with advanced, metastatic, or recurrent non-squamous non-small-cell lung cancer and those with metastatic colorectal cancer.
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Cancer cells

Isofol stock drops 27% as PFS reporting issue emerges in phase III cancer trial

Dec. 6, 2021
By Cormac Sheridan
Shares in Isofol Medical AB dropped by 27% on Dec. 6 as the company informed investors that its ongoing phase III trial of arfolitixorin in metastatic colorectal cancer would not reach the predefined number of events needed to demonstrate a statistically significant effect on progression-free survival (PFS) based on the study’s present statistical plan.
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Tot Biopharm’s first ADC bevacizumab gets China lung cancer approval

Dec. 2, 2021
By Doris Yu
Tot Biopharm International Co. Ltd.’s self-developed Pusintin (bevacizumab), a biosimilar to Roche Holding AG’s Avastin, has won marketing approval from China’s NMPA. It was approved for the treatment of patients with advanced, metastatic, or recurrent non-squamous non-small-cell lung cancer and those with metastatic colorectal cancer.
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Illustration of DNA, digestive system

Coloscape demonstrates 100% specificity for colorectal cancer

Oct. 27, 2021
By Annette Boyle
Diacarta Inc.’s diagnostic assay, Coloscape, could be the first to meet the Centers for Medicare and Medicaid Service (CMS)’s strict standards for Medicare coverage of a liquid biopsy for colorectal cancer screening if results seen in a Plos One study are borne out in larger trials and the test gets the nod from the FDA. That is a lot of ifs, but the study posted strong results: 100% specificity and 92.2% sensitivity for cancer and 95% specificity and 62.5% sensitivity for precancerous lesions.
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Colonoscopy illustration showing endoscope, polyps in colon

Independent study confirms AI-assisted colonoscopies reduce rate of missed lesions

Sep. 30, 2021
By David Ho
Shanghai Wision AI Co. Ltd. (Wision AI) has shared positive data from a first-of-its-kind study on the use of artificial intelligence (AI) computer-aided polyp detection (CADe) system during colorectal cancer screening in a U.S. patient population. Published in the journal Clinical Gastroenterology and Hepatology, it marks the world’s first external independent randomized controlled trial of AI in the medical field conducted in the U.S.
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Cancer cell and DNA

Tumor suppressor p53 is inactivated by lncRNA

July 16, 2021
By John Fox
A long noncoding RNA (lncRNA), the RNA component of mitochondrial RNA-processing endoribonuclease, was shown to promote the growth and proliferation of colorectal cancer cells by inhibiting activity of the tumor suppressor protein p53 in a Chinese study led by oncologists Fudan University Shanghai Cancer Center.
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Colorectal cancer illustration

Geneoscopy launches pivotal trial of RNA-based at-home colorectal cancer screening test

July 12, 2021
By Meg Bryant
Diagnostics startup Geneoscopy Inc. has enrolled the first patients its pivotal CRC-PREVENT clinical trial. The interventional study will assess the safety and efficacy of the company’s noninvasive, at-home, multifactor RNA screening test for the prevention of colorectal cancer.
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Ultivision AI software image

Docbot lands a healthy $4M in series A financing

May 24, 2021
By Annette Boyle
A check up by Khosla Ventures determined that Docbot Inc. was healthy enough for the prominent biotech investor to take the lead in a $4 million series A round. The new funds bring the artificial intelligence company to a total of $8.5 million in capital raised to date. Other participants included Bold Capital Partners, Collaborative Fund and Boutique Venture Partners.
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