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Home » mRNA vaccines

Articles Tagged with ''mRNA vaccines''

Woman about to receive a vaccine
Immune

CSPC’s HPV mRNA vaccine candidate cleared to enter clinic in China

Nov. 13, 2024
CSPC Pharmaceutical Group Ltd.’s SYS-6026 has obtained clearance from China’s National Medical Products Administration (NMPA) to enter clinical trials for the treatment of high-grade squamous intraepithelial lesions associated with human papillomavirus (HPV) type 16 or 18.
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Colorized scanning electron micrograph of mpox virus (red) on the surface of infected VERO E6 cells (green).
Infection

MPXV-1103, a quadrivalent mpox mRNA vaccine, exhibits safety and efficacy

Oct. 9, 2024
Researchers from University of Science and Technology of China (USTC) published data for a novel multivalent mRNA mpox vaccine candidate, MPXV-1103.
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Vaccine vial and syringe
Infection

mRNA-1769 provides better protection against lethal mpox

Sep. 26, 2024
Researchers from Moderna Inc. and affiliated organizations presented preclinical data for the novel mRNA-lipid nanoparticle (LNP) vaccine, mRNA-1769, against mpox virus.
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Stocks rise along with concerns of global mpox outbreak

Aug. 27, 2024
By Jennifer Boggs
Following the World Health Organization’s escalation of mpox to a public health emergency of international concern on Aug. 14 and the emergence of what appears to be a more severe strain of the orthopoxvirus, the spotlight has focused on a handful of companies working on vaccines and antivirals. Shares of Geovax Labs Inc., Emergent Biosolutions Inc. and Tonix Pharmaceuticals Inc. were all trading up Aug. 19.
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Stocks rise along with concerns of global mpox outbreak

Aug. 20, 2024
By Jennifer Boggs
Following the World Health Organization’s escalation of mpox to a public health emergency of international concern on Aug. 14 and the emergence of what appears to be a more severe strain of the orthopoxvirus, the spotlight has focused on a handful of companies working on vaccines and antivirals. Shares of Geovax Labs Inc., Emergent Biosolutions Inc. and Tonix Pharmaceuticals Inc. were all trading up Aug. 19.
Read More

Stocks rise along with concerns of global mpox outbreak

Aug. 19, 2024
By Jennifer Boggs
Following the World Health Organization’s escalation of mpox to a public health emergency of international concern on Aug. 14 and the emergence of what appears to be a more severe strain of the orthopoxvirus, the spotlight has focused on a handful of companies working on vaccines and antivirals. Shares of Geovax Labs Inc., Emergent Biosolutions Inc. and Tonix Pharmaceuticals Inc. were all trading up Aug. 19.
Read More
Needle syringe with a vaccine vial.
Immune

CSPC Pharmaceutical obtains Chinese approval to advance mRNA vaccine for RSV into clinic

July 12, 2024
CSPC Pharmaceutical Group Ltd. has received clearance from China’s National Medical Products Administration (NMPA) to conduct clinical trials in China with SYS-6016, the company’s mRNA respiratory syncytial virus (RSV) vaccine.
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Infection

AD-66810 siRNA shows antiviral efficacy in preclinical HBV infection model

June 10, 2024
Previous studies have found that the effectiveness of vaccines can be increased with the knockdown of HBsAg using a small interfering RNA (siRNA). The efficacy of a bivalent mRNA vaccine in combination with the siRNA AD-66810, which targets the X gene expression in the hepatitis B virus (HBV) genome, was tested in a murine model of AAV/HBV by scientists from Clearb Therapeutics Inc.
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AI-generated image of person in hazmat suit in poultry farm with chickens out of focus in the background
Infection

Preclinical H5 mRNA vaccine immunizes and prevents mortality

June 7, 2024
A preclinical trial in mice and ferrets of an experimental mRNA vaccine against the H5 highly pathogenic avian influenza (HPAI) virus generated neutralizing antibodies and prevented severe illness and mortality of the animals.
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Brain cancer illustration
Cancer

‘Onion structure’ vaccine triggers immune system against glioblastoma

May 13, 2024
By Subhasree Nag
Researchers from the University of Florida have developed a novel mRNA cancer vaccine that aims to reprogram the immune system to target and attack cancer cells effectively. The study led by Elias Sayour reported a new mRNA vaccine design where the mRNA payload was wrapped into a multilamellar vesicle within an onion-like hierarchical structure. The findings were published in the May 9, 2024 issue of Cell.
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