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Home » mRNA vaccines

Articles Tagged with ''mRNA vaccines''

Immune

Gates Foundation investment supports Transimmune’s work on enhancing mRNA vaccines

Sep. 21, 2023
Transimmune AG has been awarded a $5 million investment from the Bill & Melinda Gates Strategic Investment Fund that will be used to leverage Transimmune’s physiologically induced dendritic cells (phDCs) to enhance the potency of mRNA vaccines in infectious diseases. The initial focus will be on a therapeutic vaccine for people with HIV.
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RNA strand
Immune

Biontech and CEPI partner to develop mRNA mpox vaccine candidates

Sep. 18, 2023
Biontech SE and the Coalition for Epidemic Preparedness Innovations (CEPI) have established a strategic partnership to advance mRNA-based vaccine candidates with the development of BNT-166 for the prevention of mpox (formerly monkeypox).
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Vaccination
Infection

Lemonex receives approval of IND application for LEM-mR203

Aug. 10, 2023
Lemonex Inc. announced that the IND application for its mRNA vaccine candidate LEM-mR203 has been approved by the Korean Ministry of Food and Drug Safety (MFDS) on July 21, 2023. The company plans to evaluate LEM-mR203 as potential treatment for COVID-19, with the planned phase I clinical trial being designed to assess its safety and immunogenicity in healthy adults at Seoul National University Hospital, Korea.
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Electron micrograph of red blood cell infected with Plasmodium falciparum surrounded by knobless uninfected blood cells.
Infection

New mRNA malaria vaccine could be more effective than antibody strategies targeting liver memory T cells

July 27, 2023
An mRNA vaccine candidate that acts in the liver by recruiting memory T cells could be the key against malaria, according to a study in mice that demonstrated its efficacy by including a natural killer T (NKT) cell agonist.
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Red blood cell infected with malaria parasites
Infection

Ocean Biomedical outlines programs targeting PfGARP to tackle malaria

July 12, 2023
Ocean Biomedical Inc. has announced a multi...
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Immuno-oncology

Defence Therapeutics engineers Accum-mRNA cancer vaccine

April 12, 2023
Defence Therapeutics Inc. says it has successfully established a strategy conjugating mRNA molecules to Accum, the company’s core technology that enables precision delivery of vaccine antigens or antibody-drug conjugates in their intact form to target cells.
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COVID-19 vaccine and syringe with flag of China

China greenlights CSPC’s mRNA COVID-19 vaccine for emergency use

March 28, 2023
By Zhang Mengying
CSPC Pharmaceutical Group Ltd.’s COVID-19 mRNA vaccine, SYS-6006, has been included for emergency use by the NMPA, the company said on March 22, marking the first domestically developed COVID-19 mRNA vaccine approved for use in China.
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China greenlights CSPC’s mRNA COVID-19 vaccine for emergency use

March 23, 2023
By Zhang Mengying
CSPC Pharmaceutical Group Ltd.’s COVID-19 mRNA vaccine, SYS-6006, has been included for emergency use by the NMPA, the company said on March 22, marking the first domestically developed COVID-19 mRNA vaccine approved for use in China.
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Cancer cell targeted in crosshairs
Newco news

Likang cleared for China’s first clinical trial testing personalized neoantigen-targeted cancer vaccine

March 21, 2023
By Doris Yu
Likang Life Sciences Holdings Ltd. received approval from China’s NMPA to start a clinical trial of its candidate, LK-101 injection, for advanced solid tumors. The company claims this is the first personalized neoantigen vaccine and mRNA editing product to enter the clinic in China.
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3D printed model of a human papillomavirus particle
Immuno-oncology

Virally driven cancers are mRNA vaccines’ first, and next, frontier

March 6, 2023
By Nuala Moran
In a striking demonstration of how the success of mRNA vaccines against COVID-19 has opened up the potential of the technology in cancer, mice that cleared a tumor after a single administration of an mRNA vaccine, also cleared a second tumor without receiving further immunization. This display of potent immunogenicity formed part of a head-to-head study of three different mRNA technology platforms in human papillomavirus (HPV)-16 associated tumors.
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