In a deal that could total about $602 million, Syndax Pharmaceuticals Inc. will collaborate with Incyte Corp. to develop and develop axatilimab, Syndax’s anti-CSF-1R monoclonal antibody. Syndax is to receive $117 million up front, a $35 million equity investment and could bring in another $350 million in regulatory, development and commercial milestone payments.
The axolotl, which can regenerate many of its body parts, was the inspiration for Walking Fish Therapeutics Inc., which just closed on a $50 million series A financing to advance its B-cell therapies for oncology, rare disease, regenerative medicine, autoimmune disease and recombinant antibody production.
Sanofi SA has added to its general medicines portfolio with a $1.9 billion acquisition of Kadmon Holding Inc. and its recently-approved graft-vs.-host disease drug Rezurock (belumosudil).