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Home » Authors » Annette Boyle

Articles by Annette Boyle

11-8-Abbott-Amplatzer-Amulet.png
TCT 2021

In head-to-head trial, it’s Watchman by a nose

Nov. 8, 2021
By Annette Boyle
Two studies presented at the 33rd Transcatheter Cardiovascular Therapeutics (TCT) conference directly compared Boston Scientific Corp.’s Watchman 2.5 and Watchman Flx to Abbott Laboratories’ Amplatzer Amulet device. Both showed Amulet had less than half as many leaks, but the clinical impact of the lower rate remained unclear.
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Ivantis Inc.’s Hydrus microstent

Alcon sees its way back into MIGS market with Ivantis acquisition

Nov. 8, 2021
By Annette Boyle
Alcon AG plans to acquire Ivantis Inc. for $475 million at closing, regaining a significant position in the lucrative minimally invasive glaucoma surgery (MIGS) space through the addition of the Hydrus microstent device to its ophthalmology portfolio. In addition to the up-front payment, the deal includes additional unspecified contingent payments dependent on achievement of certain milestones. The transaction is expected to close in the first quarter of 2022.
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Illustration of TAVR device
TCT 2021

Five years on, TAVR with self-expanding valve matches SAVR outcomes

Nov. 5, 2021
By Annette Boyle
It has long been known that patients recover more quickly from transcatheter aortic valve replacement (TAVR) than from open-heart surgery for valve replacement (SAVR) and results at two years looked good, too, with very similar outcomes. The question remained what happens in the longer term?
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M&A cityscape

Trendlines sells Orthospin to Synthe for $79.5M

Nov. 4, 2021
By Annette Boyle
Trendlines Group Ltd. reported the acquisition of its portfolio company Orthospin Ltd. by Synthes GmbH, a division of Depuy Synthes, the orthopedics company of Johnson & Johnson (J&J), for $79.5 million in cash. Johnson & Johnson’s involvement in the company goes back to July 2018, when J&J Innovation (JJDC) led the company’s series A round.
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Image of smarphone showing Allara app

Allara sees huge demand for PCOS diagnostic with 10,000 women on waitlist

Nov. 3, 2021
By Annette Boyle
Allara Health Inc. officially launched its diagnostic test for polycystic ovary syndrome (PCOS) this week, but word of mouth has already established a waitlist of more than 10,000 women. The diagnostic tool evaluates a full panel of hormonal and metabolic markers, which are used with patient-reported symptoms, to diagnose the increasingly common condition.
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Man looking at Physiq smartwatch on wrist

Physiq and Purdue develop infection-detection watch

Nov. 2, 2021
By Annette Boyle
As a counterpoint to the raft of wellness-promoting smartwatches, Purdue University and Physiq Inc. have developed a smartwatch algorithm that flags illness. A year after launching their co-development program, the two organizations reported they have created an algorithm designed for smartwatches that enables detection of early signs of infection. The algorithm is already in use in a number of Physiq’s customers’ applications, Physiq Chief Scientific Officer Stephan Wegerich told BioWorld.
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3D illustration demonstrating LIGHT next-generation proton therapy system

Flash and LIGHT illuminate the path ahead for radiotherapy

Nov. 1, 2021
By Annette Boyle
A brighter future awaits radiotherapy if Flash and LIGHT live up to their promise. Announcements made last week by Varian Medical Systems and Advanced Oncotherapy plc indicate results should be seen soon. Varian reported that the first human clinical trial of Flash, Fast-01, completed its treatment phase last week at the Cincinnati Children’s/University of Cincinnati Health Proton Therapy Center. Advanced Oncotherapy plc presented results from a modeling study of Linac for Image Guided Hadron Therapy (LIGHT) technology at the American Society for Radiation Oncology (ASTRO) 2021 Annual Meeting demonstrating that LIGHT enables both the high, super-quick dose delivery of Flash and good conformality of dose delivery to tumor tissue.
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Image of human vasculature model

3D Systems acquires Volumetric for up to $400M, expands organ bioprinting program

Oct. 29, 2021
By Annette Boyle
3D Systems Inc. acquired Volumetric Biotechnologies Inc. as part of its plan to expand its organ bioprinting program. The deal entails a $45 million upfront payment with an additional $355 million linked to meeting milestones “planned between now and 2035, and aligned with key points in the development process,” Volumetric President and CEO Jeffrey Graves told BioWorld. Houston-based Volumetric has focused on building replacement organs through bioprinting and created an approach that produces complex vasculature using light-based bioprinting.
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Hinge Health participant at home using wearable shoulder sensors, mobile app

Hinge gets a leg up with $600M investment in digital musculoskeletal solution

Oct. 28, 2021
By Annette Boyle
Digital musculoskeletal health company Hinge Health Inc. kicked its fundraising into high gear this year, reporting $400 million in a series E round and $200 million in a secondary investment today. It closed a $300 million series D just last January. The San Francisco-based company has now raised more than $1 billion and achieved a valuation in excess of $6.2 billion. Returning investors Tiger Global and Coatue Management led the series E, while new investors Alkeon and Whale Rock took a stake in the company with their $200 million. Investors in the series D and previous rounds included Atomico, Insight Partners, Quadrille, 11.2 Capital, Lead Edge Capital, Bessemer Venture Partners and Heuristic Capital.
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Illustration of DNA, digestive system

Coloscape demonstrates 100% specificity for colorectal cancer

Oct. 27, 2021
By Annette Boyle
Diacarta Inc.’s diagnostic assay, Coloscape, could be the first to meet the Centers for Medicare and Medicaid Service (CMS)’s strict standards for Medicare coverage of a liquid biopsy for colorectal cancer screening if results seen in a Plos One study are borne out in larger trials and the test gets the nod from the FDA. That is a lot of ifs, but the study posted strong results: 100% specificity and 92.2% sensitivity for cancer and 95% specificity and 62.5% sensitivity for precancerous lesions.
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