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Home » Authors » Randy Osborne

Articles by Randy Osborne

Some Assembly required: Beigene finds HBV partner in $540M deal

July 21, 2020
By Randy Osborne
The two-year standstill provision in Assembly Biosciences Inc.’s potential $540 million pact with Beigene Ltd. to advance hepatitis B virus (HBV) therapies was “highly negotiated,” said Jason Okazaki, Assembly’s chief legal and business officer.
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Some Assembly required: Beigene finds HBV partner in $540M deal

July 20, 2020
By Randy Osborne
The two-year standstill provision in Assembly Biosciences Inc.’s potential $540 million pact with Beigene Ltd. to advance hepatitis B virus (HBV) therapies was “highly negotiated,” said Jason Okazaki, Assembly’s chief legal and business officer.
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Phage bids increasing Locus of interest as Armata cuts water

July 17, 2020
By Randy Osborne
Armata Pharmaceuticals Inc.’s recent $15 million award for a three-year program from the U.S. Department of Defense to partially fund a phase Ib/II study added to the already growing resurgence of notice for phage-based therapeutics, with even big pharma starting to take heed.
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IPO, coins, upward arrow

Anton check-off: Long story short, Relay IPO proves Dynamo at $400M

July 16, 2020
By Randy Osborne
Robust financial markets continue to fuel the industry despite gloom over the COVID-19 pandemic, with Relay Therapeutics Inc. pricing its upsized, 20 million-share IPO at $20 per unit to reap $400 million.
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3D illustration of virus with RNA inside

Shoot (up) the messenger: COVID-19 mRNA vaccine prospects bearing not-bad news

July 15, 2020
By Randy Osborne
An editorial yesterday in The New England Journal of Medicine (NEJM) marveled that “the world has now witnessed the compression of six years of work into six months,” and went on to ask the question that’s on everyone’s pandemic-wrenched mind: “Can the vaccine multiverse do it again, leading to a reality of a safe, efficacious COVID-19 vaccine for the most vulnerable in the next six [months]?”
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Coronavirus, lungs, hand holding stethoscope

India ink: Equillium shares deep in the black after COVID-19 data from partner

July 14, 2020
By Randy Osborne
Although details are yet to come, Equillium Inc.’s chief medical officer, Krishna Polu, told BioWorld that the company will move “urgently and expeditiously” to set up another experiment testing itolizumab in COVID-19 now that Bangalore, India-based partner Biocon Ltd. has unveiled positive phase II results with the CD6-targeting agent. Shares of Equillium (NASDAQ:EQ) closed at $26.50, up $23.31, or 731%, after trading as high as $27.05. “We recognize we have to do a robust study,” said Bruce Steel, CEO of the La Jolla, Calif.-based firm. Talks with the FDA about design come next, but the clinical bid will “very likely include sites outside the U.S.,” where the need is high and where there is “somewhat less competition for patients,” he said.
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Tumor necrosis factor (TNF), a cytokine involved in inflammation processes

AD not in-‘soluble’ after all? Street likes Inmune’s bet on next-gen TNF

July 14, 2020
By Randy Osborne
Inmune Bio Inc. CEO Raymond Tesi told BioWorld his firm is taking an “oncology-style” approach to Alzheimer’s disease (AD) as the firm tests next-generation tumor necrosis factor (TNF) inhibitor XPro-1595 against neuroinflammation.
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Coronavirus, lungs, hand holding stethoscope

India ink: Equillium shares deep in the black after COVID-19 data from partner

July 13, 2020
By Randy Osborne
Although details are yet to come, Equillium Inc.’s chief medical officer, Krishna Polu, told BioWorld that the company will move “urgently and expeditiously” to set up another experiment testing itolizumab in COVID-19 now that Bangalore, India-based partner Biocon Ltd. has unveiled positive phase II results with the CD6-targeting agent.
Read More
IPO puzzle pieces

Nkarta’s killer (cell) IPO bags $252M, trades high as Poseida proves seaworthy, too

July 10, 2020
By Randy Osborne
Two California companies – Nkarta Inc. and Poseida Therapeutics Inc. – scored impressive IPOs but with decidedly different post-pricing performance, as Wall Street showed its enthusiasm for the former’s natural killer (NK) cell research by pushing shares (NASDAQ:NKTX) up 166%, to close July 10 at $47.90, an increase of $29.90.
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Handshake, businessmen holding dollar sign, lightbulb

HER2-fore undisclosed: Zymeworks mum on ZW-49 as Merck, BMS deals widen

July 9, 2020
By Randy Osborne
Zymeworks Inc.’s business update – which included a new, potential $891 million deal for multispecific antibody drugs with longtime partner Merck & Co. Inc. – drew mixed reviews from Wall Street, especially with regard to phase I prospect ZW-49.
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