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Home » Authors » Brian Orelli

Articles by Brian Orelli

Ligand Dusts Off Lasofoxifene, Signs 2 Deals for Pfizer Castoff

July 29, 2013
By Brian Orelli
A few years after Ligand Pharmaceuticals Inc. regained the rights to its selective estrogen receptor modulator (SERM) lasofoxifene from Pfizer Inc., the company has dusted off the osteoporosis drug and found new parties interested in moving the molecule forward.
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IPOs Hot, but Ocera Chooses Reverse Merger to Go Public

July 22, 2013
By Brian Orelli
The IPO window has turned into a sliding glass door with biotechs seizing the opportunity to tap the public markets. According to BioWorld Snapshots, 19 biotechs have hit the U.S. markets since the beginning of the year. And there are quite a few others building their books hoping to price in the coming weeks.
Read More

After Rough Year, the Future Looks Positive for Drug Sales

July 15, 2013
By Brian Orelli
Last year wasn't kind to pharmaceutical companies; loss of patent protection and a weaker dollar resulted in declining drug sales for seven out of the top 10 pharmaceutical companies.
Read More

Having IPO as Option Can Help Drive Deals

July 8, 2013
By Brian Orelli
The frothy initial public offering (IPO) market is helping companies raise capital in the public market. According to data from BioWorld Snapshots, 18 IPOs of drug companies this year raised an aggregate of more than $1.3 billion. (See BioWorld Today, July 2, 2013.)
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Q2 VC Investments Skyrocket Fueled by Open IPO Window?

July 2, 2013
By Brian Orelli
What a difference a quarter makes. Three months ago, I was lamenting about how venture capital investing was off to a slow start in 2013. After tallying the totals for the second quarter, it looks like the first quarter was more of a pause than a trend.
Read More

JDRF Funds Development of Stable, Pumpable Glucagon

July 1, 2013
By Brian Orelli
Diabetic pumps work well for delivering insulin to reduce blood sugar levels, but insulin is only one half of the blood sugar regulation that the pancreas is responsible for. In healthy individuals, the organ also releases glucagon, a hormone responsible for signaling to the liver to act in the opposite direction, raising blood sugar levels.
Read More

IPO Window Open, but Back Door Still an Option

June 24, 2013
By Brian Orelli
SAN DIEGO – The initial public offering (IPO) window has been thrown wide open with many biotechs doing their best impression of a NASCAR driver quickly jumping through the window after a fiery crash.
Read More

More Than One Way to Build a Biotech Company

June 19, 2013
By Brian Orelli
SAN DIEGO – At a session at the recent Calbio meeting, biotech executives from multiple companies explained how they got their start-ups off the ground. Be it capital-efficient virtual biotechs, strategic partnerships, venture capital funding or initial public offerings (IPOs), the message was clear: There's more than one way to build a biotech.
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J&J Doing its Best VC Imitation With Incubators, Entrepreneurs

June 17, 2013
By Brian Orelli
Johnson & Johnson has jumped into the early stage development pool with both feet. With the opening of its California Innovation Center based in Menlo Park earlier this month, the New Brunswick, N.J.-based company has established regional innovation centers, incubators, and entrepreneurs in residence to get J&J closer to early stage products that might be licensed or acquired by the health-care giant.
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Earnouts and Back-Ended Deals Expected to Continue

June 14, 2013
By Brian Orelli
SAN DIEGO – At a Calbio session, Cambell Alliance, the business consulting segment of Inventiv Health Inc., presented its survey of business development professionals.
Read More
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