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Home » Authors » Brian Orelli

Articles by Brian Orelli

Resverlogix Spins Out Platform To Make Tidy M&A Package

April 15, 2013
By Brian Orelli
Resverlogix Corp. announced last week that it's spinning out its epigenetics platform into RVX Therapeutics Inc., leaving its ApoA-I stimulating drug candidate, RVX-208, with the parent company.
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Slow Start to VC Investments in 2013, Spec Pharma Swells

April 2, 2013
By Brian Orelli
Did all the venture capitalists get washed out to sea by Superstorm Sandy? Maybe they all followed in Benedict's footsteps and resigned? Because they sure weren't doing very many deals in the first quarter.
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Deal Terminations Jump in Q1 as Partners Change Priorities

April 1, 2013
By Brian Orelli
According to data from Deloitte Recap LLC, there were 11 deals terminated in the first quarter of 2013, a number that is on pace to blow through the 30 terminated deals last year and the 31 terminations the year before.
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Long Wait for Data, Galena Buys Drug to Go Commercial

March 25, 2013
By Brian Orelli
Galena Biopharma Inc. has a bit of a wait ahead of it. The biotech initiated a Phase III trial testing NeuVax (nelipepimut-S) as an adjuvant breast cancer treatment at the beginning of 2012.
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Multiple Strategies Employed To Build Early Stage Pipelines

March 15, 2013
By Brian Orelli

Successfully developing drugs is the ultimate goal of pharmaceutical companies, but the downside is that the pipeline requires constant replenishing. The early stage drought was made worse by the merger of large pharmaceutical companies; as the pipelines came together, the later-stage compound usually got priority when there was redundancy.


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Acura Asks Pharmacists to Join Fight Against Meth

March 11, 2013
By Brian Orelli
Acura Pharmaceuticals Inc. recently launched Nexafed, its version of pseudoephedrine that uses the biotech's abuse-deterrent technology to help disrupt the drug's conversion to methamphetamine. Acura is focusing its marketing message for the over-the-counter decongestant on pharmacists.
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Third IPO Window in 15 Years Looks Nothing Like Other Two

March 4, 2013
By Brian Orelli
SAN DIEGO – The life science industry has experienced three windows of opportunity to go public in the past 15 years. The first window lasted just three years from 1998 to 2000, producing 50 initial public offerings (IPOs). The second included a whopping 92 IPOs, running from mid-2003 to 2007. The most recent window, which officially started in mid-2009, has produced only 38 IPOs despite being longer than the first and approaching the length of the second.
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Pharma Offers Insights on Partnering: Focused Is Better

March 1, 2013
By Brian Orelli
SAN DIEGO – In a session at the third annual Global Life Science Partnering Conference put on by Southern California life sciences industry organization BIOCOM, representatives from large pharmaceutical companies offered insights for biotechs looking to partner.
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Stem Cell Therapy Moves to Reinvent Itself, Raise Value

Feb. 25, 2013
By Brian Orelli
After seeing its clinical program stall following the failure of a Phase IIb trial testing NTx-265 in acute stroke, Stem Cell Therapeutics Corp. is reinventing itself. (See BioWorld Today, May 26, 2010.)
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Jennerex's Pexa-Vec Attacks Tumors Through 3 Mechanisms

Feb. 19, 2013
By Brian Orelli
Pexa-Vec (JX-594), developed by San Francisco-based Jennerex Inc., is a triple cancer killer. A publication in Cancer Research confirms anti-angiogenesis is part of Pexa-Vec's mechanism of action to attack tumors.
Read More
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