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Home » Authors » Lee Landenberger

Articles by Lee Landenberger

Medday’s confirmatory phase III in MS missteps

March 11, 2020
By Lee Landenberger
In a second phase III trial for treating progressive forms of multiple sclerosis (MS), designed to confirm the successful first trial, Medday Pharmaceuticals SA’s investigational MD-1003 failed to hit its primary and secondary endpoints.
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Silverback edges toward IND and clinic with a $78.5M series B

March 11, 2020
By Lee Landenberger
Privately held Silverback Therapeutics Inc. continued its drive toward the clinic with an oversubscribed series B financing of $78.5 million to support its lead candidate, an anti-HER2 antibody conjugated to a TLR8 agonist for treating moderate or high HER2-expressing solid tumors.
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FDA Approved stamp with blister pack

Competition aplenty as Novartis’ Isturisa is FDA-approved to treat Cushing’s disease

March 9, 2020
By Lee Landenberger
With the FDA approval of Novartis AG’s Isturisa (osilodrostat), an oral treatment for adults with Cushing’s disease, Recordati SpA, of Milan, is planning its U.S. market launch for the second or third quarter of this year. Recordati, which acquired Isturisa’s worldwide rights from Novartis in October for $390 million, expects sales to peak at $100 million annually.
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FDA approves Novartis’ Isturisa to treat Cushing’s disease

March 9, 2020
By Lee Landenberger
Bare feet
Newco news

Palvella completes enrollment for rare disease study

March 6, 2020
By Lee Landenberger
Palvella Therapeutics Inc. has completed enrollment of its phase II/III trial for treating adults with pachyonychia congenita, a rare disease that eventually leads patients to a life of chronic pain and severe problems with walking.
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Newco news

The stars shine on Orionis as it embarks on a deal with Novartis

March 5, 2020
By Lee Landenberger
Orionis Biosciences Inc. has begun a four-year collaboration with Novartis AG to discover and design small-molecule therapeutics such as protein degraders that target several therapeutic areas, including cancer. The agreement’s terms include research funding a convertible note investment, royalties and potential clinical milestones.
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In the coronavirus fight, Vir and Alnylam expand RNAi agreement

March 4, 2020
By Lee Landenberger
Vir Biotechnology Inc. and Alnylam Pharmaceuticals Inc. are expanding an infectious disease collaboration begun three years ago to take on the coronavirus. The effort now includes developing and commercializing RNAi therapies targeting SARS-CoV-2, the virus that triggers COVID-19, by developing siRNAs identified by Alnylam.
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Abpro further commits to Asia in $1.1B bispecific deal

March 3, 2020
By Lee Landenberger
Abpro Therapeutics Inc. has granted an exclusive license to Abpro Bio Co. Ltd., the former Ugint Co. Ltd., to develop and commercialize two bispecific antibodies in Asian markets, including greater China, Japan and South Korea.
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Hands holding puzzle pieces with digital globe overlay

Gilead grows its immuno-oncology portfolio with $4.9B acquisition of Forty Seven

March 2, 2020
By Lee Landenberger
Gilead Sciences Inc. will acquire Forty Seven Inc. for $4.9 billion, or $95.50 per share in cash, bringing Gilead magrolimab, an anti-CD47 monoclonal antibody being developed to treat several cancers, including myelodysplastic syndrome (MDS), acute myeloid leukemia (AML) and diffuse large B-cell lymphoma (DLBCL).
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Gilead grows its immuno-oncology portfolio with $4.9B acquisition of Forty Seven

March 2, 2020
By Lee Landenberger
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