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Home » Authors » Lee Landenberger

Articles by Lee Landenberger

Tackling infectious diseases, Appili closes $7.7M public offering and pursues collaborations

Feb. 21, 2020
By Lee Landenberger
Infectious disease has been rough going for all comers the past few years, as companies have floundered. Appili Therapeutics Inc.’s CEO, Armand Balboni saw the troubles others encountered with the indication and also saw companies with thin pipelines struggle, but it hasn’t stopped him from forging on.
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Newco news

Reinvented Coimmune has a new IND and two clinical trials

Feb. 19, 2020
By Lee Landenberger
It’s been a rapid year of change for Coimmune Inc., which was incorporated only 12 months ago and now has FDA approval of an IND clearing the way for a phase IIb trial using CMN-001 to treat advanced metastatic renal cell carcinoma (mRCC).
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Doctor examining patient's hand
Newco news

Zhittya gains approval for phase I Parkinson’s trial in Mexico

Feb. 14, 2020
By Lee Landenberger
Privately held Zhittya Genesis Medicine Inc. received approval from Mexico’s Comisión Federal para la Protección contra Riesgos Sanitarios (Cofepris) to begin a phase I trial at the Zambrano Hospital in Monterrey for patients with Parkinson’s disease.
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Chalkboard illustration: question mark, gears, lightbulb, target, rocket
Newco news

With a $2M SBIR grant, Eumentis launches to target Alzheimer’s, autism spectrum disorders

Feb. 13, 2020
By Lee Landenberger
Mark Tepper, the founder of newly launched Eumentis Therapeutics Inc., plans to use the company’s recent $2 million Small Business Innovation Research (SBIR) grant to fund IND-enabling studies for EM-036, a nitro-aminoadamantane N-methyl-D-aspartate receptor antagonist to treat Alzheimer's disease and autism spectrum disorders.
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Newco news

Pinning hopes on autophagy, Pinpoint raises $1M

Feb. 12, 2020
By Lee Landenberger
Christian Peters, CEO of the newly launched and privately held Pinpoint Therapeutics Inc., said he has a relatively unusual pedigree that allows him a unique perspective in drug development. That combination of working in academia and in the corporate sphere has given him a more well-rounded view than most.
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Coins, stock chart illustration

Three of a perfect pair: Volastra launches with a $12M financing

Feb. 11, 2020
By Lee Landenberger
The three founders of newly launched Volastra Therapeutics Inc. had plenty in common when they decided to create the company. Their offices happened to be a half block apart on 69th Street in midtown Manhattan. Their interests in oncology were similar but each approached the disease from different angles.
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Anxious balance: Biohaven’s troriluzole misses its primary endpoint while rimegepant could be a blockbuster

Feb. 10, 2020
By Lee Landenberger
Top-line results from Biohaven Pharmaceutical Holding Co.’s phase III trial of troriluzole against placebo in treating generalized anxiety disorder (GAD) failed to hit its primary endpoint, prompting the company CEO to say the poor results support halting development plans for the glutamate modulator as a monotherapy in GAD.
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Oncology: Enhertu, liso-cel, sacituzumab govitecan

Is it finally their time? Two ADCs for cancer make the blockbuster list

Feb. 10, 2020
By Lee Landenberger
Two of three oncology drugs selected for blockbuster status in the Cortellis Drugs to Watch analysis are antibody-drug conjugates (ADCs), highly targeted cancer therapies designed to leave the healthy cells be and zap the bad ones. What once was a dead end for development has morphed into a competitive space with 57 ADC candidates for cancer indications in phase I or later trials, according to Cortellis.
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Newco news

Sonoma to develop regulatory T-cell therapies with its $40M series A

Feb. 7, 2020
By Lee Landenberger
Privately held Sonoma Biotherapeutics Inc. plans to take its newly raised $40 million series A financing to develop regulatory T-cell therapies to control inflammatory responses in autoimmune diseases such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis.
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PTSD chalk silhouette, man holding head

Stressful: Tonix halts enrollment for its phase III in PTSD

Feb. 6, 2020
By Lee Landenberger
An interim analysis of the phase III Recovery study of TNX-102 SL (cyclobenzaprine HCl sublingual tablets) for treating post-traumatic stress disorder (PTSD) compelled Tonix Pharmaceuticals Holding Corp. to halt enrollment in the clinical trial.
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