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Fri, May 23, 2025

Omics

  • Omics
    • Genomics
    • Metabolomics
    • Proteomics
Home » Topics » Science » Omics
  • Biology cell division illustration
    April 25, 2025
    By Mar de Miguel

    Germline variants’ impact on pan-cancer proteome

    A large-scale study has revealed the impact of germline variants on proteins in 10 cancer types. Scientists from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) conducted a precision proteogenomic analysis in a pan-cancer study with data from 1,064 patients, identifying tumor heterogeneity and tumorigenesis associated with heritable genetic alterations.
  • Biology cell division illustration
    April 22, 2025
    By Mar de Miguel

    Germline variants’ impact on pan-cancer proteome

    A large-scale study has revealed the impact of germline variants on proteins in 10 cancer types. Scientists from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) conducted a precision proteogenomic analysis in a pan-cancer study with data from 1,064 patients, identifying tumor heterogeneity and tumorigenesis associated with heritable genetic alterations. The results provide a broad view of cancer risk that could be useful for patient stratification and the design of prevention strategies.
  • Gynecology pcos polycystic ovary syndrome
    April 4, 2025
    By Mar de Miguel

    First atlas of the endometrium with polycystic ovary syndrome

    Although the causes of polycystic ovary syndrome (PCOS) are unclear, researchers know this condition leads to endometrial dysfunction in women who have hormonal imbalances, and insulin resistance. Now, a study led by scientists at the Karolinska Institutet in Sweden has revealed the cellular and genetic differences that distinguish this disorder in the first atlas of the human endometrium during the proliferative phase of the menstrual cycle.
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Authors

  • Mark McCarty
  • Annette Boyle
  • Liz Hollis
  • Catherine Longworth
  • Mar de Miguel
  • Subhasree Nag
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