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Sat, Jul 19, 2025

American Heart Association Scientific Sessions

Home » Topics » Conferences » American Heart Association Scientific Sessions
  • Heart scientific overlay
    Dec. 4, 2024

    MTX-652 attenuates TAC-induced cardiac dysfunction in vivo

    Data from a preclinical study assessing Mission Therapeutics Ltd.’s clinical-stage USP30 inhibitor MTX-652, for the prevention of transverse aortic constriction (TAC)-induced cardiac hypertrophy and remodeling, were recently presented.
  • Lungs and bronchi
    Nov. 29, 2024

    GPR39 blockade prevents hypoxia-induced pulmonary artery hypertension

    Recent findings have unveiled that 15-HETE is the endogenous agonist for G protein-coupled receptor 39 (GPR39) in vascular smooth cells, so researchers hypothesized that GPR39 could work as a therapeutic target in pulmonary arterial hypertension and its deletion might prevent the development of the disease.
  • Heart ai
    Nov. 28, 2024

    E-Therapeutics’ B4GALT1-targeting Galomic siRNA demonstrates prolonged duration of action

    Potent siRNAs against B4GALT1 were designed in silico and screened in vitro (Huh7 cells, primary mouse, human hepatocytes) as well as in vivo (C57BL/6 mice) for the selection of a lead Galomic siRNA.
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