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Home » neurodegenerative diseases

Articles Tagged with ''neurodegenerative diseases''

Brain illustration

International researchers develop dementia diagnostic algorithm

July 26, 2021
By Annette Boyle
Researchers from Finland and Italy published a biomarker-based algorithm for the diagnosis of dementia in the journal Diagnostics. The algorithm enables clinicians to distinguish between various neurodegenerative diseases with shared clinical presentations and select appropriate treatment. The algorithm relies primarily on blood biomarker measurements to diagnose the type of dementia much earlier than is possible with the diagnostic tools in use today.
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Blood-brain barrier illustration
Newco news

Neuvasq looking to blood-brain barrier to target neurological disease

July 12, 2021
By Nuala Moran
LONDON – Neuvasq Biotechnologies has launched with a €20 million (US$23.7 million) series A to take forward a new approach to treating neurological disorders by reversing age- or injury-related damage to the blood-brain barrier.
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Muna Therapeutics gets $73M series A to develop new therapies for neurodegenerative diseases

July 9, 2021
By Nuala Moran
LONDON – Another Novo Seeds start-up has graduated, with Muna Therapeutics ApS closing a $73 million series A to take forward small-molecule treatments for neurodegenerative diseases.
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Amyloid plaques forming between neurons
Newco news

New GAIM in town, as Amyl rakes in $22M to target misfolded proteins

June 16, 2021
By Nuala Moran
LONDON – Newco Amyl Therapeutics Ltd. has raised €18.3 million (US$22.3 million) in a series A, to pick up the baton on a technology for neutralizing toxic protein aggregates by binding to their amyloid folds.
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Neurology illustration

Infantile Parkinson’s can give clues to adult kind, but so can LSDs

June 8, 2021
By Anette Breindl and Nuala Moran
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases, and the role of ?-synuclein accumulation and the subsequent death of dopaminergic neurons in the midbrain have long been recognized as key steps in the disease. Progress in understanding genetic risk factors, meanwhile, has uncovered multiple genetic risk factors. Even though aging is the single biggest risk factor for PD, there are versions of the disorder that affect children.
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Brain and neural networks

New PPARgamma agonist shows promise in neurodegenerative diseases

June 7, 2021
By John Fox
The new peroxisome proliferator-activated receptor gamma (PPARgamma) agonist leriglitazone (hydroxypioglizatone; Minoryx Therapeutics), has a better profile for treating neurodegenerative diseases, such as X-linked adrenoleukodystrophy (X-ALD), than similar drugs, including pioglitazone (Actos; Takeda).
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Cumulus headset

Cumulus raises £6M for EEG treatment tracking system

May 7, 2021
By Nuala Moran
LONDON – Cumulus Neuroscience Ltd. has raised £6 million (US$8.3 million) to advance development of its home use wearable headset for tracking response to treatment in clinical trials in psychiatric disorders and neurodegenerative diseases, including Alzheimer’s.
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Gene therapy startup Capsida banks $140M in series A round plus Abbvie deal

April 29, 2021
By Cormac Sheridan
Capsida Biotherapeutics Inc., a gene therapy startup focused on advanced capsid engineering to generate tissue-selective vectors, emerged from stealth with $50 million in series A funding and another $90 million in cash from a strategic collaboration and option agreement in neurodegenerative disease with Abbvie Inc.
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Merck, Amathus collaborating on neurodegenerative therapies in a $500M+ deal

March 17, 2021
By Lee Landenberger
Merck & Co. Inc. is bringing in Amathus Therapeutics Inc. to collaborate on developing small molecules to treat neurodegenerative disease. The deal is one of several in the past 18 months that has expanded Merck’s presence in the space.
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Mina takes RNA platform to the CNS in potential $267M Servier deal

Jan. 21, 2021
By Cormac Sheridan
DUBLIN – Mina Therapeutics Ltd. is extending its small activating RNA (saRNA) technology into the central nervous system through a partnership with Les Laboratoires Servier SAS that could be worth as much as €220 million (US$266.5 million) in up-front and milestone payments.
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