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Home » antivirals

Articles Tagged with ''antivirals''

Infection

Immunic presents XAVI-101, a novel DHODH inhibitor with broad-spectrum antiviral properties

May 18, 2023
Dihydroorotate dehydrogenase (DHODH) is an enzyme ubiquitously expressed in all tissues whose inhibition has proven effective in preventing viral replication. Previous knowledge on DHODH inhibitor vidofludimus calcium demonstrated that this compound inhibits viral replication of DNA, RNA and retroviruses and induces innate immune responses that lead to an antiviral state thus inhibiting virus reactivation.
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Infection

Nanjing Zhihe Pharmaceutical discovers new prodrugs for viral infections

May 4, 2023
Nanjing Zhihe Pharmaceutical Technology Co. Ltd. has described nucleotide derivatives acting as prodrugs reported to be useful for the treatment of viral infections.
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Colorized transmission electron micrograph of SARS-CoV-2.
Infection

Discovery of novel virus fusion inhibitors with potent preclinical anti-SARS-CoV-2 activity

April 13, 2023
Researchers from Georgia State University presented the discovery and preclinical evaluation of novel antiviral candidates against the SARS...
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Virus and drug illustration

WHO pushes for more access to COVID-19 drugs

April 12, 2023
By Mari Serebrov
As country after country downshifts out of pandemic mode, the need for affordable COVID-19 therapies continues, especially in middle-income countries that are not included in current voluntary licensing arrangements. To meet that need, the WHO is calling on manufacturers of those drugs to extend the geographic scope of their licensing agreements to allow competition and price reductions. 
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Virus and drug illustration

WHO pushes for more access to COVID-19 drugs

April 11, 2023
By Mari Serebrov
As country after country downshifts out of pandemic mode, the need for affordable COVID-19 therapies continues, especially in middle-income countries that are not included in current voluntary licensing arrangements. To meet that need, the World Health Organization (WHO) is calling on manufacturers of those drugs to extend the geographic scope of their licensing agreements to allow competition and price reductions so the treatments can be used where they’re needed most.
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Pros and cons of broader COVID-19 IP waiver aired at USITC hearing

April 4, 2023
By Mari Serebrov
During the first round of discussion at its two-day hearing on a World Trade Organization proposal to expand the intellectual property (IP) waiver from COVID-19 vaccines to diagnostics and therapies, the U.S. International Trade Commission (USITC) got an earful from both sides of the debate.
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Pros and cons of broader COVID-19 IP waiver aired at USITC hearing

March 29, 2023
By Mari Serebrov
During the first round of discussion at its two-day hearing on a World Trade Organization proposal to expand the intellectual property (IP) waiver from COVID-19 vaccines to diagnostics and therapies, the U.S. International Trade Commission (USITC) got an earful from both sides of the debate.
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Infection

Nanjing Zhihe Pharmaceutical presents new cytidine derivatives for viral infections

March 24, 2023
Nanjing Zhihe Pharmaceutical Technology Co. Ltd. has divulged cytidine derivatives reported to be useful for the treatment of viral infections.
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Colorized transmission electron micrograph of SARS-CoV-2 (UK B.1.1.7 variant).
Infection

Researchers find mSWI/SNF complexes play role in SARS-CoV-2 infection

March 23, 2023
Current prophylactic and therapeutic approaches for SARS-CoV-2 are effective, but the need for new approaches with broad activity makes virus-host interactions an essential piece to look at.
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WTO logo

Decision to expand WTO COVID-19 waiver drags on as pandemic wanes

Feb. 7, 2023
By Mari Serebrov
Any decision on whether to expand a five-year World Trade Organization (WTO) waiver of intellectual property rights for COVID-19 vaccines to diagnostics and therapies likely will be delayed longer than proponents had hoped. WTO members originally were scheduled to vote on expanding the waiver in December, but the deadline was extended indefinitely when key members, including the U.S., pushed for a delay.
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