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Home » antivirals

Articles Tagged with ''antivirals''

Colorized transmission electron micrograph of SARS-CoV-2.
Infection

Kinetin identified as a potential new SARS-CoV-2 antiviral compound

Feb. 6, 2023
Researchers from Fundacao Oswaldo Cruz (Fiocruz) have evaluated kinetin (MB-905) as an antiviral against SARS-CoV-2.
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Oral medication
Infection

Tonix Pharmaceuticals to develop TNX-3900 series of oral antivirals

Feb. 3, 2023
Tonix Pharmaceuticals Holding Corp. has announced it plans to develop the TNX-3900 series of oral antivirals as monotherapy or in combination with other antivirals, following an agreement whereby it has acquired all of the assets of Healion Bio Inc., including its entire portfolio of next-generation antiviral technology assets.
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WTO logo

Decision to expand WTO COVID-19 waiver drags on as pandemic wanes

Feb. 2, 2023
By Mari Serebrov
Any decision on whether to expand a five-year World Trade Organization (WTO) waiver of intellectual property rights for COVID-19 vaccines to diagnostics and therapies likely will be delayed longer than proponents had hoped. WTO members originally were scheduled to vote on expanding the waiver in December, but the deadline was extended indefinitely when key members, including the U.S., pushed for a delay.
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Infection

Suzhou Spring-Sea Bio-Pharmaceuticals presents prodrugs of NHC to treat viral infections

Jan. 11, 2023
Suzhou Spring-Sea Bio-Pharmaceuticals Co. Ltd. has divulged prodrugs of N4-hydroxycytidine (NHC) reported to be useful for the treatment of viral infections.
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Infection

Emory University describes new NHC analogues for viral infections

Dec. 22, 2022
Emory University has identified deuterated and/or methylated N4-hydroxycytidine (NHC) analogues reported to be useful for the treatment of viral infections.
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Red wooden approved stamp

Shionogi scores emergency approval for Japan’s first domestic COVID-19 oral antiviral

Dec. 13, 2022
By Tamra Sami
Shionogi & Co. Ltd.’s orally administered COVID-19 antiviral, 3CL protease inhibitor Xocova (ensitrelvir/S-217622), scored emergency regulatory approval from Japan’s Ministry of Health, Labor and Welfare for SARS-CoV-2 infection, and the Japanese government has agreed to purchase 1 million courses of Xocova for domestic supply of the antiviral.
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Microscope and coronavirus illustration
Infection

Pfizer and Clear Creek collaborate on SARS-CoV-2 PLpro inhibitors for COVID-19

Dec. 7, 2022
Pfizer Inc. and Clear Creek Bio Inc. have entered into a research collaboration and exclusive license agreement to advance the discovery and development of potential inhibitors of the SARS-CoV-2 papain-like protease (PLpro) for the oral treatment of COVID-19.
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Viruses
Newco news

Atriva taking host-targeted antiviral approach into basket study

Nov. 11, 2022
By Jennifer Boggs
Atriva Therapeutics GmbH, a small firm founded in 2015 to develop a host-targeted antiviral approach for treating respiratory viral infections, seems to have found itself in thick of it. As the U.S. CDC and other health agencies warn of an uptick in respiratory viral infections – the so-called “tripledemic” of influenza, respiratory syncytial virus and COVID-19 – the German company is gearing up to launch a basket trial testing lead candidate zapnometinib in all three indications.
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Right on the nose: Rigimmune’s acquisition of Subintro helps close the stem-loop

Oct. 27, 2022
By Lee Landenberger
With its acquisition of Subintro Ltd., Rigimmune Inc. put a building block in place to further its development of stem-loop RNA therapeutics that selectively activate the innate immune sensor RIG-I. Subintro specializes in development and delivery of antiviral therapeutics for respiratory diseases caused by RNA viruses, including influenza, rhinovirus and SARS-CoV-2. Subintro’s technology allows the company to consider topical and nasal delivery.
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India map on technology concept background

UK creates national monkeypox research consortium

Oct. 21, 2022
By Nuala Moran
The U.K. is launching a coordinated national program of research into the unprecedented outbreak of monkeypox that has spread across Europe and North America – regions where the disease is not endemic – over the past six months. Taking a lead from the SARS-CoV-2 playbook, there will be work to sequence the viral genome and to study how it is evolving, linking this to changes in the transmission and pathology of the virus.
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