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Home » Alzheimer’s disease

Articles Tagged with ''Alzheimer’s disease''

New Japan drug approvals: cancer, insomnia, Alzheimer’s and more

Sep. 26, 2024
By Marian (YoonJee) Chu
Japan’s Ministry of Health, Labour and Welfare granted new drug approvals and expanded indications for conditions like cancer, insomnia and Alzheimer’s disease (AD) Sept. 24, including Eli Lilly and Co.’s Kisunla (donanemab) for early symptomatic AD.
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Down-syndrome karyotype, female, unlabeled, isolated on black background; trisomy 21 illustration
Neurology/psychiatric

ECNP 2024: At both ends of life, improving cognition in Down syndrome

Sep. 26, 2024
By Anette Breindl
At the 2024 European College of Neuropsychopharmacology (ECNP) Congress, researchers have presented work that could lead to ways to boost brain development and prevent neurodegeneration in individuals with Down syndrome.
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Down-syndrome karyotype, female, unlabeled, isolated on black background; trisomy 21 illustration

ECNP 2024: At both ends of life, improving cognition in Down syndrome

Sep. 24, 2024
By Anette Breindl
At the 2024 European College of Neuropsychopharmacology (ECNP) Congress, researchers have presented work that could lead to ways to boost brain development and prevent neurodegeneration in individuals with Down syndrome.
Read More
Elderly woman holding illustration of brain with missing puzzle piece
Neurology/psychiatric

FO-4-15, an anti-AD candidate with reduced neurotoxicity and enhanced neuroprotective effects

Sep. 20, 2024
Researchers from the Chinese Academy of Medical Sciences reported the discovery of the 1,2,4-oxadiazole derivative FO-4-15 for the treatment of Alzheimer’s disease (AD).
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AI-generated art of brain connections

Novo Nordisk seeks to repurpose GLP-1s, again, for the brain

Sep. 17, 2024
By Marian (YoonJee) Chu
As Novo Nordisk A/S and Eli Lilly and Co. go head-to-head in the U.S. and Chinese glucagon-like peptide-1 receptor agonists (GLP-1RA) market for diabetes and obesity, Novo Nordisk is in innovator gear once more with leading studies of GLP-1s in Alzheimer’s disease.
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AI-generated art of brain connections

Novo Nordisk seeks to repurpose GLP-1s, again, for the brain

Sep. 13, 2024
By Marian (YoonJee) Chu
As Novo Nordisk A/S and Eli Lilly and Co. go head-to-head in the U.S. and Chinese glucagon-like peptide-1 receptor agonists (GLP-1RA) market for diabetes and obesity, Novo Nordisk is in innovator gear once more with leading studies of GLP-1s in Alzheimer’s disease.
Read More
Neurology/psychiatric

MK-4334 ameliorates cognition in Alzheimer’s disease models

Sep. 12, 2024
Neuroinflammation underlies neurodegeneration in Alzheimer’s disease (AD) and other brain disorders. The stimulation of nicotinic α7 receptors, involved in the regulation of neuroinflammation, has shown efficacy in improving memory and learning in AD models.
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Brain illustration
Neurology/psychiatric

QED-701 results in significant phenotypic improvements in models of neurodegenerative disease

Sep. 9, 2024
It has been previously demonstrated that the activation of spleen tyrosine kinase (SYK) contributes to processes that are central to the pathogenesis of neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).
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Concept art for cells receptors, inhibitors
Neurology/psychiatric

Mid-Atlantic, Accelero collaborate to identify USP30 inhibitors

Sep. 5, 2024
Mid-Atlantic Biotherapeutics Inc. and Accelero Biostructures have entered into a research collaboration to identify novel USP30 inhibitors for neurological disorders and other indications.
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Fosgo death blow? Athira theory intact post-phase II/III AD bust

Sep. 4, 2024
By Randy Osborne
Athira CEO Mark Litton said the firm is “evaluating all the options” after disclosing top-line results from its phase II/III Lift-AD clinical trial of fosgonimeton (fosgo), a hepatocyte growth factor-positive modulator, in patients with mild to moderate Alzheimer’s disease (AD). Javier San Martin, chief medical officer, said the company will schedule “a conversation at the right time” with the U.S. FDA.
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