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Home » Alzheimer’s disease

Articles Tagged with ''Alzheimer’s disease''

Neurology/psychiatric

European scientists unveil new EPHX2/QPCTL inhibitors for Alzheimer’s disease

Oct. 2, 2024
Researchers at QPS Clinical Services GmbH and Universitat de Barcelona have divulged dual bifunctional epoxide hydrolase 2 (EPHX2; sEH) and glutaminyl-peptide cyclotransferase-like protein (QPCTL; IsoQC) inhibitors reported to be useful for the treatment of Alzheimer’s disease.
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New Japan drug approvals: cancer, insomnia, Alzheimer’s and more

Oct. 1, 2024
By Marian (YoonJee) Chu
Japan’s Ministry of Health, Labour and Welfare granted new drug approvals and expanded indications for conditions like cancer, insomnia and Alzheimer’s disease (AD) Sept. 24, including Eli Lilly and Co.’s Kisunla (donanemab) for early symptomatic AD.
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Transdermal patch on arm

China approves Sino Biopharm’s patch for Alzheimer’s disease

Oct. 1, 2024
By Tamra Sami
China’s National Medical Products Administration has approved Sino Biopharmaceutical Ltd.’s rivastigmine transdermal patch to treat mild to moderate Alzheimer’s disease. Developed by Sino Biopharm, the patch is the first domestically produced rivastigmine transdermal patch approved for marketing. Rivastigmine is a cholinesterase inhibitor used for the treatment of Alzheimer’s disease.
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Inflammatory microglia from a female brain in a mouse model of Alzheimer's disease
Neurology/psychiatric

In Alzheimer’s, risk gene combination affects females more

Oct. 1, 2024
By Anette Breindl
The E4 variant of the APO gene, the R47H variant of the TREM2 gene, and female sex are three of the strongest risk factors for the development of Alzheimer’s disease (AD). By combining all three of them in a mouse model of tauopathy, researchers at Weill Cornell Medical School have identified microglial inflammation and senescence as processes that occurred more strongly in female mice as tauopathy developed.
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Transdermal patch on arm

China approves Sino Biopharm’s patch for Alzheimer’s disease

Sep. 26, 2024
By Tamra Sami
China’s National Medical Products Administration has approved Sino Biopharmaceutical Ltd.’s rivastigmine transdermal patch to treat mild to moderate Alzheimer’s disease. Developed by Sino Biopharm, the patch is the first domestically produced rivastigmine transdermal patch approved for marketing. Rivastigmine is a cholinesterase inhibitor used for the treatment of Alzheimer’s disease.
Read More

New Japan drug approvals: cancer, insomnia, Alzheimer’s and more

Sep. 26, 2024
By Marian (YoonJee) Chu
Japan’s Ministry of Health, Labour and Welfare granted new drug approvals and expanded indications for conditions like cancer, insomnia and Alzheimer’s disease (AD) Sept. 24, including Eli Lilly and Co.’s Kisunla (donanemab) for early symptomatic AD.
Read More
Down-syndrome karyotype, female, unlabeled, isolated on black background; trisomy 21 illustration
Neurology/psychiatric

ECNP 2024: At both ends of life, improving cognition in Down syndrome

Sep. 26, 2024
By Anette Breindl
At the 2024 European College of Neuropsychopharmacology (ECNP) Congress, researchers have presented work that could lead to ways to boost brain development and prevent neurodegeneration in individuals with Down syndrome.
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Down-syndrome karyotype, female, unlabeled, isolated on black background; trisomy 21 illustration

ECNP 2024: At both ends of life, improving cognition in Down syndrome

Sep. 24, 2024
By Anette Breindl
At the 2024 European College of Neuropsychopharmacology (ECNP) Congress, researchers have presented work that could lead to ways to boost brain development and prevent neurodegeneration in individuals with Down syndrome.
Read More
Elderly woman holding illustration of brain with missing puzzle piece
Neurology/psychiatric

FO-4-15, an anti-AD candidate with reduced neurotoxicity and enhanced neuroprotective effects

Sep. 20, 2024
Researchers from the Chinese Academy of Medical Sciences reported the discovery of the 1,2,4-oxadiazole derivative FO-4-15 for the treatment of Alzheimer’s disease (AD).
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AI-generated art of brain connections

Novo Nordisk seeks to repurpose GLP-1s, again, for the brain

Sep. 17, 2024
By Marian (YoonJee) Chu
As Novo Nordisk A/S and Eli Lilly and Co. go head-to-head in the U.S. and Chinese glucagon-like peptide-1 receptor agonists (GLP-1RA) market for diabetes and obesity, Novo Nordisk is in innovator gear once more with leading studies of GLP-1s in Alzheimer’s disease.
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