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Home » non-small-cell lung cancer

Articles Tagged with ''non-small-cell lung cancer''

3D illustration and light micrograph of lung cancer.

Innovent on a roll: China accepts two new NDAs for lung cancer

Nov. 27, 2023
By Tamra Sami
In less than one week, Innovent Biologics Inc. has seen two NDAs for non-small-cell lung cancer accepted for review by China’s National Medical Products Administration, and both are firsts for China. The NDA for IBI-351 under priority review marks China’s first NDA for a KRAS G12C inhibitor, and the NDA for taletrectinib is the first global submission for the ROS1 inhibitor.
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Apollomics gets China NMPA nod for lung cancer drug vebreltinib

Nov. 17, 2023
By Marian (YoonJee) Chu
The U.S. and China biotech Apollomics Inc. on Nov. 16 gained the NMPA’s conditional approval for its cellular mesenchymal-epithelial transcription inhibitor for lung cancer called vebreltinib (APL-1010) through its Beijing-based partner, Avistone Biotechnology Co. Ltd.
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Apollomics gets China NMPA nod for lung cancer drug vebreltinib

Nov. 17, 2023
By Marian (YoonJee) Chu
The U.S. and China biotech Apollomics Inc. on Nov. 16 gained the NMPA’s conditional approval for its cellular mesenchymal-epithelial transcription inhibitor for lung cancer called vebreltinib (APL-1010) through its Beijing-based partner, Avistone Biotechnology Co. Ltd.
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3D illustration of tumor
Cancer

Repare advances new PLK-4 inhibitor and POLθ inhibitor programs toward clinic

Nov. 16, 2023
Repare Therapeutics Inc. has unveiled two programs targeted to enter the clinic next year.
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3D illustration and light micrograph of lung cancer.
Cancer

MRTX-1257 enhances radiotherapy effect in preclinical setting

Nov. 13, 2023
Alone or combined with chemotherapy, radiation therapy (RT) is the standard therapeutic option for the majority of non-small-cell lung cancer (NSCLC) cases. Unfortunately, the proportion of patients that experience local-regional relapse can reach 50% of cases. Data from previous investigations link KRAS mutations to radioresistance.
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Cancer

Blueprint Medicines divulges new EGFR inhibitors for cancer

Nov. 2, 2023
Blueprint Medicines Corp. has synthesized EGFR (HER1; erbB1) inhibitors reported to be useful for the treatment of cancer, particularly non-small-cell lung cancer.
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ESMO 2023: Immutep’s LAG-3 immunotherapy shows 35.5 months overall survival in NSCLC

Oct. 24, 2023
By Tamra Sami
Immutep Ltd.’s lead candidate, eftilagimod (IMP-321, efti), a lymphocyte activation gene-3 (LAG-3) fusion protein and major histocompatibility complex class II agonist, delivered an overall survival benefit of 35.5 months in the TACTI-002 trial that combined efti with Merck & Co. Inc.’s Keytruda (pembrolizumab) as first-line treatment of non-small-cell lung cancer (NSCLC) at two years follow-up.
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AI generated illustration of lungs in the human body
Cancer

ESMO 2023: New approaches to old targets, including HER2 and p53

Oct. 24, 2023
By Mar de Miguel
Some cancers with a poor prognosis have had no new treatments in decades. Advances in the genetic characterization of these tumors now offer a range of possibilities for the development of new therapies that could completely change the quality of life and survival of these patients.
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AI generated illustration of lungs in the human body
Cancer

ESMO 2023: New approaches to old targets, including HER2 and p53

Oct. 23, 2023
By Mar de Miguel
Some cancers with a poor prognosis have had no new treatments in decades. Advances in the genetic characterization of these tumors now offer a range of possibilities for the development of new therapies that could completely change the quality of life and survival of these patients.
Read More
Lung cancer illustration

With positive phase II interim data in NSCLC, Abion to advance MET-TKI to combo trial

Oct. 17, 2023
By Marian (YoonJee) Chu
Precision cancer biotech Abion Inc. announced a positive interim phase II readout for ABN-401, its novel c-mesenchymal-epithelial transition (c-MET)-targeting tyrosine kinase inhibitor (TKI) for advanced non-small-cell lung cancer (NSCLC), lighting a runway to its next trial as a combination regimen.
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