Blocking the CCR5 receptor on neurons enhanced the recovery from stroke and traumatic brain injury in animal studies, and patients with the delta32 mutation in CCR5, which renders the receptor nonfunctional, showed better recovery after mild to moderate stroke in the TABASCO clinical trial.

In findings that show a way to target tumors with mutations in isocitrate dehydrogenase 1 (IDH1), as well as bring new insights into the complexity of its effects, researchers have discovered that inhibiting cell cycle checkpoints or the DNA damage response could be a treatment option for gliomas with IDH1 mutations.

Researchers at the University of Wisconsin have discovered a link between fragile X syndrome (FXS) and Huntingtin (Htt) protein, better known for its role in Huntington's disease (HD). 

Scientists at the University of Salamanca have demonstrated that free radicals or reactive oxygen species (ROS) produced by astrocytes had a beneficial effect on brain metabolism. 

Researchers have shown that T cells produced the neurotransmitter acetylcholine to affect blood vessel dilation, which helped them control chronic infections. The work was published in the Feb. 8, 2019, issue of Science.

In results that are simple in one sense and profound in another, researchers at Texas A&M University have demonstrated that application of growth factor bone morphogenetic protein 9 (BMP9) could regenerate a joint in mice after an amputation.