The engineered protein 3K3A-APC, a variant of activated protein C, is in clinical trials for stroke and has demonstrated neuroprotective effects in animal models of other neurological diseases as well. Now, researchers from the University of Southern California have found that 3K3A-APC was effective at preventing behavioral deficits and neuronal damage in an animal model of Alzheimer's disease (AD).
Researchers from the University of Washington and Stanford University have used bioinformatics to develop proteins that bound to specific forms of the interleukin-2 (IL-2) receptor, but otherwise had no structural similarity to IL-2.
Researchers have identified a single nucleotide polymorphism (SNP) that affected whether the diabetes drug Avandia (rosiglitazone, GlaxoSmithKline plc) would cause a rise in cholesterol levels.
Researchers at the University of Washington have developed a "nanoscavenger" that was able to protect mice from the consequences of organophosphorus (OP) compounds.
"Let me tell you about the very rich. They are different from you and me," F. Scott Fitzgerald wrote in his short story "All the Sad Young Men," to which Ernest Hemingway had a character in "The Snows of Kilimanjaro" reply "Yes, they have more money."
